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Jose Luis Zugaza Gurruchaga

Principal Investigator

Ikerbasque Research Professor

Jose Luis Zugaza Gurruchaga

Research groups:

Contact

Correo electrĆ³nico:JoseLuis.Zugaza@ehu.eus

Tel.:(+34) 94 601 2256

Science Park of the UPV/EHU
Sede Building, 3rd floor, Barrio Sarriena, s/n
E-48940 Leioa Spain

0000-0003-2287-6671

About me

PhD Universidad de Santiago de Compostela (Spain), 1993

Our laboratory works on cell signaling in cancer and neurodegeneration.

Publications

  1. Optimized SARS-CoV-2 spike protein detection via coupling coefficient-driven fast fourier transform analysis in a peptide-functionalized fiber optic biosensor
    Arrizabalaga, Oskar; Andres, Alain CastaƱo; Zugaza, Jose L.; Zubia, Joseba
    Sensors and Actuators B: Chemical (Apr, 2025) DOI: 10.1016/j.snb.2025.137226

  2. Amyloid-Ī² Dysregulates Oligodendroglial Lineage Cell Dynamics and Myelination via PKC in the Zebrafish Spinal Cord
    Balantzategi, U.; Gaminde-Blasco, A.; Kearns, C.A.; BayĆ³n-Cordero, L.; SĆ”nchez-GĆ³mez, M.V.; Zugaza, J.L.; Appel, B.; Alberdi, E.
    GLIA (Mar, 2025) DOI: 10.1002/glia.70015

  3. The signaling landscape of insulin-like growth factor 1
    Khan, M.Z.; Zugaza, J.L.; Torres Aleman, I.
    Journal of Biological Chemistry (Jan, 2025) DOI: 10.1016/j.jbc.2024.108047

  4. The importance of muscle glycogen phosphorylase in glial cells function
    Llavero, Francisco; Zugaza, JosƩ L.
    Biochemical Society Transactions (Apr, 2024) DOI: 10.1042/BST20231058

  5. Amyloid Ī²1ā€“42 Oligomers Induce Galectinā€“1S8 Oā€“GlcNAcylation Leading to Microglia Migration
    Arrazola Sastre, Alazne; Luque Montoro, Miriam; Llavero, Francisco; Zugaza, JosƩ L.
    Cells (Jul, 2023) DOI: 10.3390/cells12141876

  6. P-Rex1 is a novel substrate of the E3 ubiquitin ligase Malin associated with Lafora disease
    Kumarasinghe, L.; Garcia-Gimeno, M. A.; Ramirez, J.; Mayor, U.; Zugaza, J. L.; Sanz, P.
    Neurobiology of Disease (Feb, 2023) DOI: 10.1016/j.nbd.2023.105998

  7. Recombinant Integrin Ī²1 Signal Peptide Blocks Gliosis Induced by AĪ² Oligomers
    Ortiz-Sanz, Carolina; Llavero, Francisco; Zuazo-Ibarra, Jone; Balantzategi, Uxue; Quintela-LĆ³pez, Tania; Wyssenbach, Ane; Capetillo-Zarate, Estibaliz; Matute, Carlos; Alberdi, Elena; Zugaza, JosĆ© L.
    International Journal of Molecular Sciences (May, 2022) DOI: 10.3390/ijms23105747

  8. Identification of Potential Muscle Biomarkers in McArdle Disease: Insights from Muscle Proteome Analysis
    GarcĆ­a-Consuegra, InĆ©s; Asensio-PeƱa, Sara; Garrido-Moraga, RocĆ­o; PinĆ³s, TomĆ s; DomĆ­nguez-GonzĆ”lez, Cristina; Santalla, Alfredo; Nogales-Gadea, Gisela; Serrano-Lorenzo, Pablo; Andreu, Antoni L.; Arenas, JoaquĆ­n; Zugaza, JosĆ© L.; Lucia, Alejandro; MartĆ­n, Miguel A.
    International Journal of Molecular Sciences (Apr, 2022) DOI: 10.3390/ijms23094650

  9. Amyloid Ī² / PKC-dependent alterations in NMDA receptor composition are detected in early stages of AlzheimerĀ“s disease
    Ortiz-Sanz, Carolina; Balantzategi, Uxue; Quintela-LĆ³pez, Tania; Ruiz, Asier; Luchena, Celia; Zuazo-Ibarra, Jone; Capetillo-Zarate, Estibaliz; Matute, Carlos; Zugaza, JosĆ© L.; Alberdi, Elena
    Cell Death & Disease (Mar, 2022) DOI: 10.1038/s41419-022-04687-y

  10. The tyrosine phosphatase hPTPRĪ² controls the early signals and dopaminergic cells viability via the P2X7 receptor
    Llavero Bernal, F.L.; Luque Montoro, M.L.; Arrazola Sastre, A.A.; Lacerda, H.M.; Zugaza, J.L.
    International Journal of Molecular Sciences (Nov, 2021) DOI: 10.3390/ijms222312936
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