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Ana Bernal Chico

Senior Researcher

Ana Bernal Chico

Contact

Email:Ana.Bernal@ehu.eus

Science Park of the UPV/EHU
Sede Building, 3rd floor, Barrio Sarriena, s/n
E-48940 Leioa Spain

About me

I graduated in Biochemistry at the University of the Basque Country in Leioa (Spain) in 2008. Following a 1-year training period at the Laboratory of Molecular Genetics (Cruces University Hospital), I started my Thesis project at the Laboratory of Neurobiology under the supervision of Dr. Susana Mato and Prof. Carlos Matute. I obtained my Ph.D. in Neuroscience at University of the Basque Country in 2014 and in 2015 I started a postdoctoral training period at the Momentum Laboratory of Molecular Neurobiology under the supervision of Prof. István Katona (Institute of Experimental Medicine, Hungarian Academy of Sciences in Budapest – KOKI/MTA), as a recipient of a postdoctoral grant from the MTA.

In 2016, I was granted a postdoctoral fellowship from the Basque Government, which supported me until January 2020. During my scientific career, I have collaborated in 6 research projects obtained in national and international competitive calls. I am co-author of 9 publications and 21 communications to national and international meetings. My work on the role of MAGL as therapeutic target in multiple sclerosis (Bernal-Chico et al., Glia 2015) has been awarded by the Spanish Society on Cannabinoid Research (SEIC 2014) and the Spanish Glia Network (RGE, III Laia Acarín Award).

I am a regular member of the SEIC, the Federation of European Neuroscience Societies (FENS), the Spanish Neuroscience Society (SENC) and I belong to the Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), as well as to Biocruces Bizkaia HRI.

Publications

  1. Autoimmune inflammation triggers aberrant astrocytic calcium signaling to impair synaptic plasticity

    Baraibar, A. M.; Colomer, T.; Moreno-García, A.; Bernal-Chico, A.; Sánchez, E.; Utrilla, C.; Serrat, R.; Soria-Gómez, E.; Rodríguez-Antigüedad, A.; Araque, A.; Matute, C.; Marsicano, G.; Mato, S.
    Brain, Behavior, and Immunity (Jul, 2024) DOI: 10.1016/j.bbi.2024.07.010
  2. Endocannabinoid signaling in brain diseases: Emerging relevance of glial cells

    Bernal-Chico, Ana; Tepavcevic, Vanja; Manterola, Andrea; Utrilla, Carmen; Matute, Carlos; Mato, Susana
    Glia (Mar, 2022) DOI: 10.1002/glia.24172
  3. Δ9-Tetrahydrocannabinol promotes oligodendrocyte development and CNS myelination in vivo

    Huerga‐Gómez, Alba; Aguado, Tania; Torre, Aníbal Sánchez-de la; Bernal‐Chico, Ana; Matute, Carlos; Mato, Susana; Guzmán, Manuel; Galve‐Roperh, Ismael; Palazuelos, Javier
    Glia (Mar, 2021) DOI: 10.1002/glia.23911
  4. Gene Expression Analysis of Astrocyte and Microglia Endocannabinoid Signaling during Autoimmune Demyelination

    Moreno-García, Álvaro; Bernal-Chico, Ana; Colomer, Teresa; Rodríguez-Antigüedad, Alfredo; Matute, Carlos; Mato, Susana
    Biomolecules (Aug, 2020) DOI: 10.3390/biom10091228
  5. P2x7 receptors control demyelination and inflammation in the cuprizone model

    Bernal-Chico, Ana; Manterola, Andrea; Cipriani, Raffaela; Katona, István; Matute, Carlos; Mato, Susana
    Brain, Behavior, & Immunity - Health (Apr, 2020) DOI: 10.1016/j.bbih.2020.100062
  6. Deregulation of the endocannabinoid system and therapeutic potential of ABHD6 blockade in the cuprizone model of demyelination

    Manterola, Andrea; Bernal-Chico, Ana; Cipriani, Raffaela; Canedo-Antelo, Manuel; Moreno-García, Álvaro; Martín-Fontecha, Mar; Pérez-Cerdá, Fernando; Sánchez-Gómez, María Victoria; Ortega-Gutiérrez, Silvia; Brown, J. Mark; Hsu, Ku-Lung; Cravatt, Benjamin; Matute, Carlos; Mato, Susana
    Biochemical Pharmacology (Nov, 2018) DOI: 10.1016/j.bcp.2018.07.042
  7. Cytosolic zinc accumulation contributes to excitotoxic oligodendroglial death: Zinc Mediates AMPA Toxicity to Oligodendrocytes

    Mato, Susana; Sánchez-Gómez, María Victoria; Bernal-Chico, Ana; Matute, Carlos
    GLIA (May, 2013) DOI: 10.1002/glia.22470