Our lab aims at deciphering of molecular mechanisms and signaling pathways responsible for oligodendrocyte proliferation, differentiation or damage and their relevance in oligodendrocyte dynamics, myelin remodeling and axonal conduction in Alzheimer´s disease. To this end, we employ a combination of molecular, imaging and electrophysiological approach in isolated cell culture, organotypic slices and acute slices, as well as in Alzheimer´s disease mouse models and brain samples of Alzheimer´s disease patients.

My main research line is amyloid-beta signalling in oligodendrocytes