Astrocytes in Alzheimer’s Disease
10
Mar
2021
A review on their pathological significance and molecular pathways
This review article is fruit of the collaboration between different laboratories and researchers in Achucarro, with Dr. Pranav Preman at VIB-KU Leuven, Belgium.
In this paper, the authors provide an overview of the origin, main functions, molecular and morphological features of astrocytes in physiological as well as pathological conditions related to Alzheimer´s disease. Authors also explore the main roles of astrocytes in the pathogenesis of Alzheimer´s disease and summarize main transcriptional changes and altered molecular pathways observed in astrocytes during the course of the disease.
