Cover in Molecular Psychiatry to a collaborative work by Juanma Encinas
The collaboration work unveiled the molecular mechanisms that explain how, as the brain ages, hippocampal neural stem cells slow down their mitotic activity and prevent their depletion.
Our colleague Juanma Encinas collaborated with Dr. Carlos Fitzsimons from the University of Amsterdam in the recently published article entitled “Circadian glucocorticoid oscillations preserve a population of adult hippocampal neural stem cells in the aging brain“ published in the prestigious journal Molecular Psychiatry and has been given de cover for the July’s issue.
This is not the first fruitful collaboration between Encinas and Fitzsimons, in a previous work, published in Aging Cell in 2019, they unveiled the molecular mechanisms that explain how, as the brain ages, hippocampal neural stem cells slow down their mitotic activity and prevent their depletion.
Following that discovery, in the recent paper the researches explain how neural stem cells increase the expression of glucocorticoid receptors to reduce their activation and their depletion.
Reference:
https://www.nature.com/mp/volumes/25/issues/7
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