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Jose Luis Zugaza Gurruchaga

Principal Investigator

Ikerbasque Research Professor

Jose Luis Zugaza Gurruchaga

Contact

Email:JoseLuis.Zugaza@ehu.eus

Tel.:(+34) 94 601 2256

Science Park of the UPV/EHU
Sede Building, 3rd floor, Barrio Sarriena, s/n
E-48940 Leioa Spain

About me

PhD Universidad de Santiago de Compostela (Spain), 1993

Our laboratory works on cell signaling in cancer and neurodegeneration.

Publications

  1. The signaling landscape of insulin-like growth factor 1

    Khan, M.Z.; Zugaza, J.L.; Torres Aleman, I.
    Journal of Biological Chemistry (Jan, 2025) DOI: 10.1016/j.jbc.2024.108047
  2. The importance of muscle glycogen phosphorylase in glial cells function

    Llavero, Francisco; Zugaza, José L.
    Biochemical Society Transactions (Apr, 2024) DOI: 10.1042/BST20231058
  3. Amyloid β1–42 Oligomers Induce Galectin–1S8 O–GlcNAcylation Leading to Microglia Migration

    Arrazola Sastre, Alazne; Luque Montoro, Miriam; Llavero, Francisco; Zugaza, José L.
    Cells (Jul, 2023) DOI: 10.3390/cells12141876
  4. P-Rex1 is a novel substrate of the E3 ubiquitin ligase Malin associated with Lafora disease

    Kumarasinghe, L.; Garcia-Gimeno, M. A.; Ramirez, J.; Mayor, U.; Zugaza, J. L.; Sanz, P.
    Neurobiology of Disease (Feb, 2023) DOI: 10.1016/j.nbd.2023.105998
  5. Recombinant Integrin β1 Signal Peptide Blocks Gliosis Induced by Aβ Oligomers

    Ortiz-Sanz, Carolina; Llavero, Francisco; Zuazo-Ibarra, Jone; Balantzategi, Uxue; Quintela-López, Tania; Wyssenbach, Ane; Capetillo-Zarate, Estibaliz; Matute, Carlos; Alberdi, Elena; Zugaza, José L.
    International Journal of Molecular Sciences (May, 2022) DOI: 10.3390/ijms23105747
  6. Identification of Potential Muscle Biomarkers in McArdle Disease: Insights from Muscle Proteome Analysis

    García-Consuegra, Inés; Asensio-Peña, Sara; Garrido-Moraga, Rocío; Pinós, Tomàs; Domínguez-González, Cristina; Santalla, Alfredo; Nogales-Gadea, Gisela; Serrano-Lorenzo, Pablo; Andreu, Antoni L.; Arenas, Joaquín; Zugaza, José L.; Lucia, Alejandro; Martín, Miguel A.
    International Journal of Molecular Sciences (Apr, 2022) DOI: 10.3390/ijms23094650
  7. Amyloid β / PKC-dependent alterations in NMDA receptor composition are detected in early stages of Alzheimer´s disease

    Ortiz-Sanz, Carolina; Balantzategi, Uxue; Quintela-López, Tania; Ruiz, Asier; Luchena, Celia; Zuazo-Ibarra, Jone; Capetillo-Zarate, Estibaliz; Matute, Carlos; Zugaza, José L.; Alberdi, Elena
    Cell Death & Disease (Mar, 2022) DOI: 10.1038/s41419-022-04687-y
  8. The tyrosine phosphatase hPTPRβ controls the early signals and dopaminergic cells viability via the P2X7 receptor

    Llavero Bernal, F.L.; Luque Montoro, M.L.; Arrazola Sastre, A.A.; Lacerda, H.M.; Zugaza, J.L.
    International Journal of Molecular Sciences (Nov, 2021) DOI: 10.3390/ijms222312936
  9. (Editorial) Cell Signaling in Neurodegeneration

    Zugaza, José L.
    International Journal of Molecular Sciences (Aug, 2021) DOI: 10.3390/ijms22168978
  10. (Review) Small gtpases of the rab and arf families: Key regulators of intracellular trafficking in neurodegeneration

    Sastre, A.A.; Montoro, M.L.; Lacerda, H.M.; Llavero, F.; Zugaza, J.L.
    International Journal of Molecular Sciences (Apr, 2021) DOI: 10.3390/ijms22094425